Characterising Human Tissue Resident T-Cells in Health and Autoimmune Disease

Point-of-care detection of fibrosis in liver transplant surgery using near-infrared spectroscopy and machine learning

VJ Sharma, JA Adegoke, M Fasulakis, A Green, SK Goh, X Peng, Y Liu, L Jackett, A Vago, EKW Poon, G Starkey, S Moshfegh, A Muthya, R D'Costa, F James, CL Gordon, R Jones, IO Afara, BR Wood, J Raman

2023-11-01

Introduction: Visual assessment and imaging of the donor liver are inaccurate in predicting fibrosis and remain surrogates for his..

Fresh human cardiac tissue for translational research: A novel method of sampling deceased organ donors

V Sharma, JAL Grant, S Gangahanumiah, A Singh, CL Gordon, F James, R D'Costa, G Starkey, J Raman

2023-06-01

Early immune pressure initiated by tissue-resident memory T cells sculpts tumor evolution in non-small cell lung cancer

CE Weeden, V Gayevskiy, C Marceaux, D Batey, T Tan, K Yokote, NT Ribera, A Clatch, S Christo, CE Teh, AJ Mitchell, M Trussart, L Rankin, A Obers, JA McDonald, KD Sutherland, VJ Sharma, G Starkey, R D'Costa, P Antippa

2023-05-08

Tissue-resident memory T (T<inf>RM</inf>) cells provide immune defense against local infection and can inhibit cancer progression...

Mechanistic Target of Rapamycin Inhibition Prevents Coronary Artery Remodeling in a Murine Model of Kawasaki Disease

AT Stock, S Parsons, DB D'Silva, JA Hansen, VJ Sharma, F James, G Starkey, R D'Costa, CL Gordon, IP Wicks

2023-02-01

Objective: Remodeling of the coronary arteries is a common feature in severe cases of Kawasaki disease (KD). This pathology is dri..

Australian Donation and Transplantation Biobank: A Research Biobank Integrated Within a Deceased Organ and Tissue Donation Program

VJ Sharma, G Starkey, R D'costa, F James, E Mouhtouris, L Davis, BZ Wang, A Vago, J Raman, LK Mackay, H Opdam, R Jones, ML Grayson, DE Martin, CL Gordon

2022-12-12

Background. We aimed to facilitate the donation of tissue samples for research by establishing a centralized system integrated in ..

Captopril, a Renin–Angiotensin System Inhibitor, Attenuates Tumour Progression in the Regenerating Liver Following Partial Hepatectomy

GE Riddiough, KA Walsh, T Fifis, G Kastrappis, BM Tran, E Vincan, V Muralidharan, C Christophi, CL Gordon, MV Perini

2022-05-01

(1) Liver regeneration following partial hepatectomy for colorectal liver metastasis (CRLM) has been linked to tumour recurrence. ..

Are NKT cells a useful predictor of COVID-19 severity?

HF Koay, NA Gherardin, THO Nguyen, W Zhang, JR Habel, R Seneviratna, F James, NE Holmes, OC Smibert, CL Gordon, JA Trubiano, K Kedzierska, DI Godfrey

2022-02-08

Intimal macrophages develop from circulating monocytes during vasculitis

AT Stock, S Parsons, VJ Sharma, F James, G Starkey, R D'Costa, CL Gordon, IP Wicks

2022-01-01

Objective: Vasculitis is characterised by inflammation of the blood vessels. While all layers of the vessel can be affected, infla..

Staff to staff transmission as a driver of healthcare worker infections with COVID-19

CL Gordon, JA Trubiano, NE Holmes, KYL Chua, J Feldman, G Young, NL Sherry, ML Grayson, JC Kwong

2021-11-01

Background: High rates of healthcare worker (HCW) infections due to COVID-19 have been attributed to several factors, including in..

Defective Severe Acute Respiratory Syndrome Coronavirus 2 Immune Responses in an Immunocompromised Individual with Prolonged Viral Replication

CL Gordon, OC Smibert, NE Holmes, KYL Chua, M Rose, G Drewett, F James, E Mouhtouris, THO Nguyen, W Zhang, L Kedzierski, LC Rowntree, BY Chua, L Caly, MG Catton, J Druce, M Sait, T Seemann, NL Sherry, BP Howden

2021-09-01

We describe severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-specific immune responses in a patient with lymphoma and ..

Holding our breath: The promise of tissue-resident memory T cells in lung cancer

C Marceaux, CE Weeden, CL Gordon, ML Asselin-Labat

2021-06-01

T cell memory is critical in controlling infection and plays an important role in anti-tumor responses in solid cancers. While eff..

Analysis of Skin-Resident Memory T Cells Following Drug Hypersensitivity Reactions

Jason A Trubiano, Claire L Gordon, Clara Castellucci, Susan N Christo, Simone L Park, Effie Mouhtouris, Katherine Konvinse, Morgan Rose, Michelle Goh, Alan S Boyd, Elizabeth J Phillips, Laura K Mackay

2020-07-01

Local heroes or villains: tissue-resident memory T cells in human health and disease

SC Sasson, CL Gordon, SN Christo, P Klenerman, LK Mackay

2020-02-01

Tissue-resident memory T (T<inf>RM</inf>) cells are increasingly associated with the outcomes of health and disease. T<inf>RM</inf..